Pharmacology for Cardiovascular Disorder

Pharmacology for Cardiovascular Disorder

Pharmacologyfor Cardiovascular Disorder

Nameof Institute

Pharmacologyfor Cardiovascular Disorder

PatientAO has a history of obesity and has recently gained 9 pounds. He hasbeen diagnosed with hypertension and hyperlipidemia. Age is a factorthat influences the patient’s pharmacokinetic and pharmacodynamicprocesses. Research shows that the aging process induces asignificant change in sensitivity to particular cardiovascularmedications. This is based on the fact that some of these medicationscause a mild effect on the patient’s receptor sites. If patient AOis elderly, he or she is bound to experience a change in the numberof receptor sites hence affecting the efficiency of the prescribeddrugs.

Sincepatient AO has hypertension, the prescribed drugs are designed tomaintain a certain blood pressure limit which means the patient mightstart to experience sudden precipitous drops in blood pressure as aresult of age-induced orthostatic pressure. Changes in thepharmacodynamic process might lead to adjustments in the drug intakeprocedure and therapy. For instance, patient AO will have to take theprescribed medications in small dosages to minimize the intensity ofthe pharmacodynamic process within the body (Arcangelo,&amp Peterson, (Eds.) (2013).For instance, his intake of the prescribed drugs will be

  • Atenolol 6.25mg daily

  • Doxazosin 4mg daily

  • Hydralazine 5mg qid

  • Sertraline 12.5mg daily

  • Simvastatin 40mg daily

Drugrelated pharmacodynamic effects will require the patient todrastically minimize his dosage so that his body is able to slowlymetabolize the medicine into the blood stream. Based on theunderstanding of the pharmacodynamic and pharmacokinetic processes,the age factor plays a major role of how patient AO will consume hisdrugs during treatment. Reducing the amount of the dosage for allthe five drugs by half so that there is possibility of drug inducedrenal toxicity and complications.

Inconclusion, pharmacokinetic and pharmacodynamic processes allowdoctors and physicians identify the patient’s bodily function andresponse to the prescribed medications. In other words, these twoprocesses provide an insight if a patient is allergic to certaindrugs or not.

References

Arcangelo,V. P., &amp Peterson, A. M. (Eds.). (2013). Pharmacotherapeutics foradvanced practice: A practical approach (3rd ed.). Ambler, PA:Lippincott Williams &amp Wilkins.&nbsp Chapter19, “Hypertension” (pp. 230–246)

LaureateEducation, Inc. (Executive Producer). (2012). Hypertension andhyperlipidemia. Baltimore, Maryland: Author.

Arcangelo,V. P., &amp Peterson, A. M. (Eds.). (2013). Pharmacotherapeutics foradvanced practice: A practical approach (3rd ed.). Ambler, PA:Lippincott Williams &amp Wilkins.&nbspChapter20, “Hyperlipidemia” (pp. 247–262)